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Article

Hemoglobin induced NO/cGMP suppression Deteriorate Microcirculation via Pericyte Phenotype Transformation after Subarachnoid Hemorrhage in Rats.

Scientific reports - 25 Feb 2016

Li Qiang, Chen Yujie, Li Bo, Luo Chunxia, Zuo Shilun, Liu Xin, Zhang John H, Ruan Huaizhen, Feng Hua

Abstract excerpt

Subarachnoid hemorrhage (SAH) usually results from ruptured aneurysm, but how leaked hemoglobin regulates the microcirculation in the pathophysiology of early brain injury after SAH is still unclear. In the present study, we sought to investigate the role and possible mechanism of hemoglobin induced pericyte phenotype transformation in the regulation of microcirculation after SAH. Endovascular perforation SAH rat...

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Identifiers

PMID: 26911739
DOI: 10.1038/srep22070
PMCID: PMC4766506

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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