Article
Comparison of three summary statistics for ranking genes in genome-wide association studies.
Statistics in medicine - 20 May 2014
Freytag Saskia, Bickeböller Heike
Abstract excerpt
Problems associated with insufficient power have haunted the analysis of genome-wide association studies and are likely to be the main challenge for the analysis of next-generation sequencing data. Ranking genes according to their strength of association with the investigated phenotype is one solution. To obtain rankings for genes, researchers can draw from a wide range of statistics summarizing the relationships...
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