Article
Gene-gene interaction filtering with ensemble of filters.
BMC bioinformatics - 15 Feb 2011
Yang Pengyi, Ho Joshua Wk, Yang Yee Hwa, Zhou Bing B
Abstract excerpt
BACKGROUND: Complex diseases are commonly caused by multiple genes and their interactions with each other. Genome-wide association (GWA) studies provide us the opportunity to capture those disease associated genes and gene-gene interactions through panels of SNP markers. However, a proper filtering procedure is critical to reduce the search space prior to the computationally intensive gene-gene interaction...
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