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Article

RAD51C--a new human cancer susceptibility gene for sporadic squamous cell carcinoma of the head and neck (HNSCC).

Oral oncology - 1 Mar 2014

Scheckenbach Kathrin, Baldus Stephan E, Balz Vera, Freund Marcel, Pakropa Petra, Sproll Christoph, Schäfer Karl-Ludwig, Wagenmann Martin, Schipper Jörg, Hanenberg Helmut

Abstract excerpt

INTRODUCTION: Head and neck squamous cell carcinomas (HNSSCs) are one of the leading causes of cancer-associated death worldwide. Although certain behavioral risk factors are well recognized as tumor promoting, there is very little known about the presence of predisposing germline mutations in HN...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24315737
DOI: 10.1016/j.oraloncology.2013.11.007
PMCID: PMC4230275

Genes

RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24315737-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

RAD51C--a new human cancer susceptibility gene for sporadic squamous cell carcinoma of the head and neck (HNSCC).PMID 24315737Read ↗

Rad51C: a novel suppressor gene modulates the risk of head and neck cancer.Semantic proximity Read ↗

Evaluation of RAD51C as cancer susceptibility gene in a large breast-ovarian cancer patient population referred for genetic testing.Semantic proximity Read ↗

Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patientsSemantic proximity Read ↗

Polymorphic Variants in 5'-UTR Regions of the RAD51 Gene are Associated With RAD51 Expression and Triple-Negative Breast Cancer (TNBC): A Case-Control Study.Semantic proximity Read ↗

RAD51C germline mutations found in Spanish site-specific breast cancer and breast-ovarian cancer families.Semantic proximity Read ↗

RAD51C germline mutations in breast and ovarian cancer cases from high-risk families.Semantic proximity Read ↗

RAD51C germline mutations in Chinese women with familial breast cancerSemantic proximity Read ↗

Identification of six pathogenic RAD51C mutations via mutational screening of 1228 Danish individuals with increased risk of hereditary breast and/or ovarian cancer.Semantic proximity Read ↗

Structural Perturbations and Destabilizing Mutations in RAD51C and RAD51D Reveal Mechanisms of Cancer RiskSemantic proximity Read ↗

Further evidence for the contribution of the RAD51C gene in hereditary breast and ovarian cancer susceptibility.Semantic proximity Read ↗

RAD51C is a susceptibility gene for ovarian cancer.Semantic proximity Read ↗

Four cancer cases with pathological germline variant RAD51D c.270_271dup.Semantic proximity Read ↗

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