Article
RAD51C--a new human cancer susceptibility gene for sporadic squamous cell carcinoma of the head and neck (HNSCC).
Oral oncology - 1 Mar 2014
Scheckenbach Kathrin, Baldus Stephan E, Balz Vera, Freund Marcel, Pakropa Petra, Sproll Christoph, Schäfer Karl-Ludwig, Wagenmann Martin, Schipper Jörg, Hanenberg Helmut
Abstract excerpt
INTRODUCTION: Head and neck squamous cell carcinomas (HNSSCs) are one of the leading causes of cancer-associated death worldwide. Although certain behavioral risk factors are well recognized as tumor promoting, there is very little known about the presence of predisposing germline mutations in HNSCC patients. METHODS: In this study, we analyzed 121 individuals with HNSCCs collected at our institution for germline...
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