Article
Conformational polymorphism of m7GTP in crystal structure of the PB2 middle domain from human influenza A virus.
PloS one - 1 Jan 2013
Tsurumura Toshiharu, Qiu Hao, Yoshida Toru, Tsumori Yayoi, Hatakeyama Dai, Kuzuhara Takashi, Tsuge Hideaki
Abstract excerpt
Influenza pandemics with human-to-human transmission of the virus are of great public concern. It is now recognized that a number of factors are necessary for human transmission and virulence, including several key mutations within the PB2 subunit of RNA-dependent RNA polymerase. The structure of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
