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Article

Characterization of the Interaction Domains between the Phosphoprotein and the Nucleoprotein of Human Metapneumovirus.

Journal of virology - 26 Jan 2022

Decool Hortense, Bardiaux Benjamin, Checa Ruano Luis, Sperandio Olivier, Fix Jenna, Gutsche Irina, Richard Charles-Adrien, Bajorek Monika, Eléouët Jean-François, Galloux Marie

Abstract excerpt

Human metapneumovirus (HMPV) causes severe respiratory diseases in young children. The HMPV RNA genome is encapsidated by the viral nucleoprotein (N), forming an RNA-N complex (NNuc), which serves as the template for genome replication and mRNA transcription by the RNA-dependent RNA polymerase (RdRp). The RdRp is formed by the association of the large polymerase subunit (L), which has RNA polymerase, capping, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34730389
DOI: 10.1128/JVI.00909-21
PMCID: PMC8791268

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Characterization of the Interaction Domains between the Phosphoprotein and the Nucleoprotein of Human Metapneumovirus.PMID 34730389Read ↗

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