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CytoMatrix for a reliable and simple characterization of lung cancer stem cells from malignant pleural effusions

9 Aug 2019

Abstract excerpt

Cancer stem cells (CSCs) are a subpopulation with the properties of extensive self-renewal, capability to generate differentiated cancer cells and resistance to therapies. We have previously shown that malignant pleural effusions (MPEs) from patients with non-small-cell lung cancer (NSCLC) represent a valuable source of cancer cells that can be grown as three-dimensional (3D) spheroids enriched for stem-like...

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PMID: 31397494
DOI: 10.1002/jcp.29121

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