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Article

DNA polymorphisms and response to treatment in patients with chronic hepatitis C: results from the HALT-C trial.

Journal of hepatology - 1 Oct 2008

Morgan Timothy R, Lambrecht Richard W, Bonkovsky Herbert L, Chung Raymond T, Naishadham Deepa, Sterling Richard K, Fontana Robert J, Lee William M, Ghany Marc G, Wright Elizabeth C, O'Brien Thomas R

Abstract excerpt

BACKGROUND/AIMS: Certain host genetic polymorphisms reportedly affect the likelihood of a sustained virological response (SVR) to interferon treatment in subjects infected with hepatitis C virus (HCV). As part of the HALT-C trial we evaluated genetic associations among patients infected with HCV genotype 1 who had failed previous interferon treatment. METHODS: SVR was determined 24 weeks after completing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18619701
DOI: 10.1016/j.jhep.2008.05.011
PMCID: PMC3903339

Genes

TNF
AGT
CCL2
EPHX1
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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