Article
Notch3 establishes brain vascular integrity by regulating pericyte number.
Development (Cambridge, England) - 1 Jan 2014
Wang Yuying, Pan Luyuan, Moens Cecilia B, Appel Bruce
Abstract excerpt
Brain pericytes are important regulators of brain vascular integrity, permeability and blood flow. Deficiencies of brain pericytes are associated with neonatal intracranial hemorrhage in human fetuses, as well as stroke and neurodegeneration in adults. Despite the important functions of brain pericytes, the mechanisms underlying their development are not well understood and little is known about how pericyte...
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