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Article

Next-generation sequencing for molecular ecology: a caveat regarding pooled samples.

Molecular ecology - 1 Feb 2014

Anderson Eric C, Skaug Hans J, Barshis Daniel J

Abstract excerpt

We develop a model based on the Dirichlet-compound multinomial distribution (CMD) and Ewens sampling formula to predict the fraction of SNP loci that will appear fixed for alternate alleles between two pooled samples drawn from the same underlying population. We apply this model to next-generation sequencing (NGS) data from Baltic Sea herring recently published by (Corander et al., 2013, Molecular Ecology,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24304095
DOI: 10.1111/mec.12609

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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