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Article

Estimating the information value of polymorphic sites using pooled sequences.

BMC genomics - 1 Jan 2014

Malde Ketil

Abstract excerpt

BACKGROUND: High-throughput sequencing is a cost effective method for identifying genetic variation, and it is currently in use on a large scale across the field of biology, including ecology and population genetics. Correctly identifying variable sites and allele frequencies from sequencing data remains challenging, in large part due to artifacts and biases inherent in the sequencing process. Selecting variants...

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PMID: 25571927
DOI: 10.1186/1471-2164-15-S6-S20
PMCID: PMC4239578

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