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Article

Differentiation of human induced pluripotent stem cells into brown and white adipocytes: role of Pax3.

Stem cells (Dayton, Ohio) - 1 Jun 2014

Mohsen-Kanson Tala, Hafner Anne-Laure, Wdziekonski Brigitte, Takashima Yasuhiro, Villageois Phi, Carrière Audrey, Svensson Maria, Bagnis Claude, Chignon-Sicard Bérengère, Svensson Per-Arne, Casteilla Louis, Smith Austin, Dani Christian

Abstract excerpt

Identification of molecular mechanisms involved in generation of different types of adipocytes is progressing substantially in mice. However, much less is known regarding characterization of brown (BAP) and white adipocyte progenitors (WAPs) in humans, highlighting the need for an in vitro model of human adipocyte development. Here, we report a procedure to selectively derive BAP and WAPs from human-induced...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24302443
DOI: 10.1002/stem.1607

Genes

BMP4
PRDM16
UCP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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