Article
A heterogeneous lineage origin underlies the phenotypic and molecular differences of white and beige adipocytes.
Journal of cell science - 15 Aug 2013
Liu Weiyi, Shan Tizhong, Yang Xin, Liang Sandra, Zhang Pengpeng, Liu Yaqin, Liu Xiaoqi, Kuang Shihuan
Abstract excerpt
A worldwide epidemic of obesity and its associated metabolic disorders raise the significance of adipocytes, their origins and characteristics. Our previous study has demonstrated that interscapular brown adipose tissue (BAT), but not intramuscular adipose, is derived from the Pax3-expressing cell lineage. Here, we show that various depots of subcutaneous (SAT) and visceral adipose tissue (VAT) are highly...
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