Article

Endotome as a Source of Human Peri-Aortic Brown Adipocytes

2026-07-06

Abstract excerpt

<h4>Summary</h4> Brown adipocytes (BAs) hold therapeutic promise for obesity and metabolic diseases. While interscapular BAs derive from Pax3 +/ Myf5 + dermomyotome, peri-aortic BAs are inferred from an unknown Pax3 +/ Myf5 - somitic origin. Here, we identify human endotome as an MYF5 -independent source of peri-aortic BAs. Through interrogating public mouse organogenesis and in-house human trunk embryoid si...

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Literature Corpus work: 95ac73bd-84fb-5889-8d3e-279bbfb58f78
DOI: 10.64898/2026.07.04.735132

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