Article
Spatially distinct functions of Clb2 in the DNA damage response.
Cell cycle (Georgetown, Tex.) - 1 Jan 2014
Machu Christophe, Eluère Raïssa, Signon Laurence, Simon Marie-Noëlle, de La Roche Saint-André Christophe, Bailly Eric
Abstract excerpt
In budding yeast four mitotic cyclins (Clb1-4) cooperate in a partially redundant manner to bring about M-phase specific events, including the apical isotropic switch that ends polarized bud growth initiated at bud emergence. How exactly this morphogenetic transition is regulated by mitotic CDKs remains poorly understood. We have taken advantage of the isotropic bud growth that prevails in cells responding to DNA...
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