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Article

Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants.

Human genetics - 1 May 2014

Yang Can, Li Cong, Kranzler Henry R, Farrer Lindsay A, Zhao Hongyu, Gelernter Joel

Abstract excerpt

Alcohol dependence (AD) is a complex psychiatric disorder that affects about 12.5 % of US adults. Genetic factors play a major role in the development of AD. We conducted a genomewide association study in 2,875 African-Americans including 1,719 AD cases and 1,156 controls. We used the Illumina Omni 1-Quad microarray, which yielded 769,498 single-nucleotide polymorphisms (SNPs) after quality control. To explore...

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Identifiers

PMID: 24297757
DOI: 10.1007/s00439-013-1399-8
PMCID: PMC3988209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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