Article
Dominant-negative E-cadherin inhibits the invasiveness of inflammatory breast cancer cells in vitro.
Journal of cancer research and clinical oncology - 1 Feb 2007
Dong Hui-Ming, Liu Gang, Hou Yi-Feng, Wu Jiong, Lu Jin-Song, Luo Jian-Min, Shen Zhen-Zhou, Shao Zhi-Ming
Abstract excerpt
E-cadherin is a transmembrane glycoprotein which mediates epithelial cell-to-cell adhesion function as a tumor suppressor and frequently loss of expression in a wide spectrum of human cancer. However, recent studies demonstrated that E-cadherin was always over-expressed in inflammatory breast cancer (IBC) specimen and cell lines, which is a clinical extreme malignancy of breast cancer. It is hypothesized that the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
