Article
[Toward identification of susceptible genes for sporadic neurodegenerative disease].
Rinsho shinkeigaku = Clinical neurology - 1 Jan 2013
Mitsui Jun
Abstract excerpt
Over the past decade, genome-wide association studies (GWASs) using common polymorphisms have been conducted to identify genetic risks associated with sporadic diseases. Although GWASs have successfully revealed numerous susceptibility genes for neurodegenerative diseases, the odds ratios associated with these risk alleles are generally low and account for only a small proportion of estimated familial clustering....
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