Article
[Molecular genetic analysis of hereditary neurodegenerative diseases].
Genetika - 1 Jun 2004
Illarioshkin S N, Ivanova-Smolenskaia I A, Markova E D, Shadrina M I, Kliushnikov S A, Zagorovskaia T V, Miklina N I, Slominskiĭ P A, Limborskaia S A
Abstract excerpt
The review summarizes the results of a decade of molecular genetic studies of several high-incidence hereditary neurodegenerative diseases, including primary parkinsonism, various forms of hereditary dystonia and ataxia, polyglutamine disorders, hepatolenticular degeneration, essential tremor, etc. Various relevant mutations were studied. The character and frequencies of particular mutations and the corresponding...
Topics
- Genetic Diseases, Inborn
- Genetics, Population
- Humans
- Mutation
- Neurodegenerative Diseases
- Russia