Article
[Overview -- exploring molecular basis of sporadic neurologic disorders].
Rinsho shinkeigaku = Clinical neurology - 1 Jan 2013
Tsuji Shoji
Abstract excerpt
During the past three decades, we have witnessed remarkable advances in our understanding of the molecular bases of hereditary neurodegenerative diseases, which have been accomplished by "positional cloning" strategies. The molecular bases of sporadic neurologic disorders, however, largely remain to be elucidated. Genome-wide association studies (GWAS) based on the "common disease-common variants hypothesis" are...
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