Article
In vitro study of phenotypical characteristics of BCG granuloma macrophages over the course of granuloma development.
Bulletin of experimental biology and medicine - 1 Sept 2013
Arkhipov S A, Shkurupy V A, Akhramenko E S, Solomatina M V, Iljine D A
Abstract excerpt
Structural and immunophenotypical characteristics of macrophages, associated with their polarization in the M1 and M2 directions of differentiation and activation, were studied in different morphological types of BCG granulomas by the expression of GM-CSF, IFN-γ, and FGFb cytokines and CD36 and CD16/32 differentiation clusters. The proportion of IFN-γ and FGFb macrophage subpopulations changed over the course of...
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