Article
Macrophage plasticity and polarization in tissue repair and remodelling.
The Journal of pathology - 1 Jan 2013
Mantovani Alberto, Biswas Subhra K, Galdiero Maria Rosaria, Sica Antonio, Locati Massimo
Abstract excerpt
Mononuclear phagocyte plasticity includes the expression of functions related to the resolution of inflammation, tissue repair and remodelling, particularly when these cells are set in an M2 or an M2-like activation mode. Macrophages are credited with an essential role in remodelling during ontogenesis. In extraembryonic life, under homeostatic conditions, the macrophage trophic and remodelling functions are...
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