Article
The one and the many: effects of the cell adhesion molecule pathway on neuropsychological function in psychosis.
Psychological medicine - 1 Jul 2014
Hargreaves A, Anney R, O'Dushlaine C, Nicodemus K K, Gill M, Corvin A, Morris D, Donohoe Gary
Abstract excerpt
BACKGROUND: Genetic studies of single gene variants have been criticized as providing a simplistic characterization of the genetic basis of illness risk that ignores the effects of other variants within the same biological pathways. Of candidate biological pathways for schizophrenia (SZ), the cell adhesion molecule (CAM) pathway has repeatedly been linked to both psychosis and neurocognitive dysfunction. Here we...
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