Article

Structurally informed evolutionary models improve phylogenetic reconstruction for emerging, seasonal, and pandemic influenza viruses

2017-12-04

Abstract excerpt

Precise estimation of genetic substitution patterns is critical for accurate reconstruction of pathogen phylogenies. Few studies of viral evolution account for variations of mutation rate across a single gene. This is especially true when considering evolution of segmented viruses where individual segments are short, encoding for few proteins. However, the structural and functional partitions of these proteins cou...

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Identifiers and source

Literature Corpus work: c820e6aa-cfaa-53ec-aa83-07608361c4e5
DOI: 10.1101/228692

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