Article
Association between a gene variant near ataxia telangiectasia mutated and coronary artery disease in men.
Diabetes & vascular disease research - 1 Jan 2014
Schiekofer Stephan, Bobak Izabela, Kleber Marcus E, Maerz Winfried, Rudofsky Gottfried, Dugi Klaus A, Schneider Jochen G
Abstract excerpt
OBJECTIVE: Type 2 diabetes is accompanied by increased mortality from coronary artery disease (CAD), but the mechanisms linking these conditions remain elusive. Hence, treatment of hyperglycaemia alone is not sufficient to avoid CAD in diabetes. Alternative views suggest that metabolic and vascular diseases share unifying cellular defects that could serve as targets for novel therapeutic strategies. Recently, a...
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