Article
Up-regulation of MSH2, XRCC1 and ATM genes in patients with type 2 diabetes and coronary artery disease.
Diabetes research and clinical practice - 1 Sept 2015
Ahmadi Amirhossein, Behmanesh Mehrdad, Boroumand Mohammad Ali, Tavallaei Mahmoud
Abstract excerpt
AIMS: Coronary artery disease (CAD) is a major problem in some patients with type 2 diabetes mellitus (T2DM). CAD has been suggested to be the main result of reduced efficacy of DNA repair systems. Analysis of the DNA repair system in patients with diabetes can potentially uncover the molecular basis of their susceptibility to the CAD. The aim of the present study was to compare the expression levels of some...
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