Article
HMGA1 is a novel candidate gene for myocardial infarction susceptibility.
International journal of cardiology - 15 Jan 2017
De Rosa Salvatore, Chiefari Eusebio, Salerno Nadia, Ventura Valeria, D'Ascoli Greta Luana, Arcidiacono Biagio, Ambrosio Giuseppe, Bilotta Francesco Luciano, Torella Daniele, Foti Daniela, Indolfi Ciro, Brunetti Antonio
Abstract excerpt
BACKGROUND: Acute Myocardial infarction (AMI), a leading cause of morbidity and mortality worldwide, is a dreadful acute complication of coronary atherosclerosis. Type 2 diabetes mellitus (T2DM) is associated with an increased risk of developing AMI. The architectural transcription factor high-mobility-group AT-hook 1 (HMGA1) has been involved in atherosclerosis, plaque formation, inflammation, and in the...
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