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Article

Polymorphism rs189037C > T in the promoter region of the ATM gene may associate with reduced risk of T2DM in older adults in China: a case control study.

BMC medical genetics - 14 Aug 2017

Ding Xiang, Hao Qiukui, Yang Ming, Chen Tie, Chen Shanping, Yue Jirong, Leng Sean X, Dong Birong

Abstract excerpt

BACKGROUND: Recent evidence indicates that ataxia telangiectasia mutated (ATM) is a cytoplasmic protein that involves in insulin signaling pathways. When ATM gene is mutated, this event appears to contribute to the development of insulin resistance and type 2 diabetes mellitus (T2DM). Up to date, little information about the relationship between ATM gene polymorphism and T2DM is available. This study aimed to...

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Identifiers

PMID: 28806901
DOI: 10.1186/s12881-017-0446-z
PMCID: PMC5557265

Genes

ATM
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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Polymorphism rs189037C > T in the promoter region of the ATM gene may associate with reduced risk of T2DM in older adults in China: a case control study.PMID 28806901Read ↗

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