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Article

ZEB1 in Pancreatic Cancer

18 Aug 2010

Abstract excerpt

Pancreatic cancer is one of the most malignant human neoplasias. On the molecular level, epithelial-mesenchymal transition (EMT) has been demonstrated to contribute to the malignant phenotype of pancreatic cancer cells. ZEB1 is a transcriptional repressor that has been identified as an inducer of EMT. A negative feedback loop between ZEB1 and microRNA-200c has been shown to regulate this EMT induction in various...

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Cancer Cells and Metastasis
MicroRNA in disease regulation
Pancreatic and Hepatic Oncology Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 24281177
DOI: 10.3390/cancers2031617

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