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Article

The cathepsin D gene exon 2 (C224T) polymorphism and sporadic Alzheimer's disease in European populations.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Aug 2005

Capurso Cristiano, Solfrizzi Vincenzo, D'Introno Alessia, Colacicco Anna M, Capurso Sabrina A, Mastroianni Franco, Liaci Maria, Vendemiale Gianluigi, Capurso Antonio, Panza Francesco

Abstract excerpt

The cathepsin D gene (CTSD) exon 2 (C224T) polymorphism has been associated with an increased risk for sporadic Alzheimer's disease (AD), but with controversial findings. We studied CTSD exon 2 (C224T) and apolipoprotein E (APOE) genotype frequencies in 168 AD patients and 218 age-matched healthy...

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Source

Identifiers

PMID: 16127101
DOI: 10.1093/gerona/60.8.991

Genes

CTSD
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16127101-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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