Article
The role of classical and alternative macrophages in the immunopathogenesis of herpes simplex virus-induced inflammation in a mouse model.
Journal of dermatological science - 1 Mar 2014
Anower A K M M, Shim Ju A, Choi Bunsoon, Kwon Hyuk Jae, Sohn Seonghyang
Abstract excerpt
BACKGROUND: The exact mechanism of the inflammatory changes occurring during the development of Behçet's disease (BD) remains unclear. OBJECTIVE: We investigated the role of classical (M1) and alternative (M2) activation of macrophages in a herpes simplex virus (HSV)-induced BD mouse model. METHODS: The classical vs. alternative activated macrophage ratio (M1/M2 ratio) was calculated by analyzing the surface...
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