Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cancer-Initiating Cells from Colorectal Cancer Patients Escape from T Cell–Mediated Immunosurveillance In Vitro through Membrane-Bound IL-4

26 Nov 2013

Abstract excerpt

Cancer-initiating cells (CICs) that are responsible for tumor initiation, propagation, and resistance to standard therapies have been isolated from human solid tumors, including colorectal cancer (CRC). The aim of this study was to obtain an immunological profile of CRC-derived CICs and to identify CIC-associated target molecules for T cell immunotherapy. We have isolated cells with CIC properties along with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Immune Cell Function and Interaction
Share to Immunotherapy and Immune Responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24277698
DOI: 10.4049/jimmunol.1301342

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cancer-Initiating Cells from Colorectal Cancer Patients Escape from T Cell–Mediated Immunosurveillance In Vitro through Membrane-Bound IL-4PMID 24277698Read ↗

Cancer-initiating cells derived from human rectal adenocarcinoma tissues carry mesenchymal phenotypes and resist drug therapies.Semantic proximity Read ↗

Establishment of Highly Tumorigenic Human Colorectal Cancer Cell Line (CR4) with Properties of Putative Cancer Stem CellsSemantic proximity Read ↗

Tumor-Initiating Cells: a criTICal review of isolation approaches and new challenges in targeting strategiesSemantic proximity Read ↗

Colorectal cancer patients-derived immunity-organoid platform unveils cancer-specific tissue markers associated with immunotherapy resistanceSemantic proximity Read ↗

Cancer Stem Cells Are Possible Key Players in Regulating Anti-Tumor Immune Responses: The Role of Immunomodulating Molecules and MicroRNAsSemantic proximity Read ↗

Phenotype molding of T cells in colorectal cancer by single-cell analysis.Semantic proximity Read ↗

What Do We Learn from Spheroid Culture Systems? Insights from Tumorspheres Derived from Primary Colon Cancer TissueSemantic proximity Read ↗

cDC2 plasticity and acquisition of a DC3-like phenotype mediated by IL-6 and PGE2 in a patient-derived colorectal cancer organoids model.Semantic proximity Read ↗

Phenotypic characterization of human colorectal cancer stem cells.Semantic proximity Read ↗

Cytotoxic T Lymphocytes Efficiently Recognize Human Colon Cancer Stem-Like CellsSemantic proximity Read ↗

Characterization of colon cancer cells: a functional approach characterizing CD133 as a potential stem cell markerSemantic proximity Read ↗

CD133 as a target for colon cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.