Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MEN1 gene mutation and reduced expression are associated with poor prognosis in pulmonary carcinoids.

The Journal of clinical endocrinology and metabolism - 1 Feb 2014

Swarts Dorian R A, Scarpa Aldo, Corbo Vincenzo, Van Criekinge Wim, van Engeland Manon, Gatti Gaia, Henfling Mieke E R, Papotti Mauro, Perren Aurel, Ramaekers Frans C S, Speel Ernst-Jan M, Volante Marco

Abstract excerpt

CONTEXT: MEN1 gene alterations have been implicated in lung carcinoids, but their effect on gene expression and disease outcome is unknown. OBJECTIVE: Our objective was to analyze MEN1 gene and expression anomalies in lung neuroendocrine neoplasms and their correlations with clinicopathologic data and disease outcome. DESIGN: We examined 74 lung neuroendocrine neoplasms including 58 carcinoids and 16 high-grade...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoid Tumor
Share to Carcinoma, Neuroendocrine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Loss of Heterozygosity

Share to Lung Neoplasms

Share to Promoter Regions, Genetic

Share to Proto-Oncogene Proteins

Share to Survival Rate

Source

Identifiers

PMID: 24276465
DOI: 10.1210/jc.2013-2782

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MEN1 gene mutation and reduced expression are associated with poor prognosis in pulmonary carcinoids.PMID 24276465Read ↗

MEN1 gene mutation analysis of high-grade neuroendocrine lung carcinomaSemantic proximity Read ↗

Gene Expression Profiling of Lung Atypical Carcinoids and Large Cell Neuroendocrine Carcinomas Identifies Three Transcriptomic Subtypes with Specific Genomic AlterationsSemantic proximity Read ↗

Lung neuroendocrine tumours: deep sequencing of the four World Health Organization histotypes reveals chromatin-remodelling genes as major players and a prognostic role for TERT, RB1, MEN1 and KMT2D.Semantic proximity Read ↗

Integrative Genomic Characterization Identifies Molecular Subtypes of Lung CarcinoidsSemantic proximity Read ↗

Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids.Semantic proximity Read ↗

Specific Genomic Alterations in High-Grade Pulmonary Neuroendocrine Tumours with Carcinoid Morphology.Semantic proximity Read ↗

Familial pulmonary carcinoid tumorsSemantic proximity Read ↗

Two distinct classes of thymic tumors in patients with MEN1 show LOH at the MEN1 locusSemantic proximity Read ↗

MEN1 deficiency leads to neuroendocrine differentiation of lung cancer and disrupts the DNA damage responseSemantic proximity Read ↗

Methylation Profiles Differ According to Clinical Characteristics in Well-Differentiated Neuroendocrine Tumors of the LungSemantic proximity Read ↗

Global gene expression in neuroendocrine tumors from patients with the MEN1 syndrome.Semantic proximity Read ↗

Mutations and allelic deletions of the MEN1 gene are associated with a subset of sporadic endocrine pancreatic and neuroendocrine tumors and not restricted to foregut neoplasms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.