Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Specific Genomic Alterations in High-Grade Pulmonary Neuroendocrine Tumours with Carcinoid Morphology.

Neuroendocrinology - 1 Jan 2021

Cros Jerôme, Théou-Anton Nathalie, Gounant Valérie, Nicolle Remy, Reyes Cécile, Humez Sarah, Hescot Ségolène, Thomas de Montpréville Vincent, Guyétant Serge, Scoazec Jean-Yves, Guyard Alice, de Mestier Louis, Brosseau Solenn, Mordant Pierre, Castier Yves, Gentien David, Ruszniewski Philippe, Zalcman Gérard, Couvelard Anne, Cazes Aurélie

Abstract excerpt

INTRODUCTION: High-grade lung neuroendocrine tumours with carcinoid morphology have been recently reported; they may represent the thoracic counterparts of grade 3 digestive neuroendocrine tumours. We aimed to study their genetic landscape including analysis of tumoral heterogeneity. METHODS: Eleven patients with high-grade (>20% Ki-67 and/or >10 mitoses) lung neuroendocrine tumours with a carcinoid morphology...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoid Tumor

Share to Carcinoma, Neuroendocrine

Share to Genomics

Share to Lung Neoplasms

Share to Mutation

Share to Neoplasm Grading

Source

Identifiers

PMID: 32015233
DOI: 10.1159/000506292

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Specific Genomic Alterations in High-Grade Pulmonary Neuroendocrine Tumours with Carcinoid Morphology.PMID 32015233Read ↗

Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids.Semantic proximity Read ↗

Lung neuroendocrine tumours: deep sequencing of the four World Health Organization histotypes reveals chromatin-remodelling genes as major players and a prognostic role for TERT, RB1, MEN1 and KMT2D.Semantic proximity Read ↗

Beyond Traditional Morphological Characterization of Lung Neuroendocrine Neoplasms: In Silico Study of Next-Generation Sequencing Mutations Analysis across the Four World Health Organization Defined GroupsSemantic proximity Read ↗

Mutational analysis of pulmonary tumours with neuroendocrine features using targeted massive parallel sequencing: a comparison of a neglected tumour group.Semantic proximity Read ↗

New Insights into the Molecular Characteristics of Pulmonary Carcinoids and Large Cell Neuroendocrine Carcinomas, and the Impact on Their Clinical ManagementSemantic proximity Read ↗

Integrative Genomic Characterization Identifies Molecular Subtypes of Lung CarcinoidsSemantic proximity Read ↗

Distinct pancreatic and neuronal Lung Carcinoid molecular subtypes revealed by integrative omic analysisSemantic proximity Read ↗

Genetic and epigenetic drivers of neuroendocrine tumours (NET)Semantic proximity Read ↗

Molecular and Morphological Profiling of Lung Cancer: A Foundation for “Next-Generation” Pathologists and OncologistsSemantic proximity Read ↗

Gene Expression Profiling of Lung Atypical Carcinoids and Large Cell Neuroendocrine Carcinomas Identifies Three Transcriptomic Subtypes with Specific Genomic AlterationsSemantic proximity Read ↗

Pathways Impacted by Genomic Alterations in Pulmonary Carcinoid Tumors.Semantic proximity Read ↗

Genomic Profiling and Clinicopathological Characteristics of Neuroendocrine Tumors of the Lung in East Asian Patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.