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Article

Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya.

Scientific reports - 25 Nov 2013

Borrmann Steffen, Straimer Judith, Mwai Leah, Abdi Abdirahman, Rippert Anja, Okombo John, Muriithi Steven, Sasi Philip, Kortok Moses Mosobo, Lowe Brett, Campino Susana, Assefa Samuel, Auburn Sarah, Manske Magnus, Maslen Gareth, Peshu Norbert, Kwiatkowski Dominic P, Marsh Kevin, Nzila Alexis, Clark Taane G

Abstract excerpt

Early identification of causal genetic variants underlying antimalarial drug resistance could provide robust epidemiological tools for timely public health interventions. Using a novel natural genetics strategy for mapping novel candidate genes we analyzed >75,000 high quality single nucleotide polymorphisms selected from high-resolution whole-genome sequencing data in 27 isolates of Plasmodium falciparum. We...

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Identifiers

PMID: 24270944
DOI: 10.1038/srep03318
PMCID: PMC3839035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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