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Article

Evaluating noncoding nucleotide repeat expansions in amyotrophic lateral sclerosis.

Neurobiology of aging - 1 Apr 2014

Figley Matthew D, Thomas Anna, Gitler Aaron D

Abstract excerpt

Intermediate-length polyglutamine expansions in ataxin 2 are a risk factor for amyotrophic lateral sclerosis (ALS). The polyglutamine tract is encoded by a trinucleotide repeat in a coding region of the ataxin 2 gene (ATXN2). Noncoding nucleotide repeat expansions in several genes are also associated with neurodegenerative and neuromuscular diseases. For example, hexanucleotide repeat expansions located in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24269018
DOI: 10.1016/j.neurobiolaging.2013.09.024
PMCID: PMC3880650

Genes

ATXN10
ATXN2
ATXN8
DMPK
JPH3
NOP56

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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