Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluating the prevalence of polyglutamine repeat expansions in amyotrophic lateral sclerosis

12 May 2011

Abstract excerpt

OBJECTIVE: Given the recent finding of an association between intermediate-length polyglutamine (polyQ) expansions in ataxin 2 and amyotrophic lateral sclerosis (ALS), we sought to determine whether expansions in other polyQ disease genes were associated with ALS. METHODS: We assessed the polyQ lengths of ataxin 1, ataxin 3, ataxin 6, ataxin 7, TBP, atrophin 1, and huntingtin in several hundred patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to Genetic Neurodegenerative Diseases
Share to Neurogenetic and Muscular Disorders Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21562248
DOI: 10.1212/wnl.0b013e31821f4447

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluating the prevalence of polyglutamine repeat expansions in amyotrophic lateral sclerosisPMID 21562248Read ↗

Ataxin-2 intermediate-length polyglutamine expansions in European ALS patientsSemantic proximity Read ↗

Ataxin-1 and ataxin-2 intermediate-length PolyQ expansions in amyotrophic lateral sclerosis.Semantic proximity Read ↗

Evaluating noncoding nucleotide repeat expansions in amyotrophic lateral sclerosis.Semantic proximity Read ↗

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS.Semantic proximity Read ↗

Ataxin-2 repeat-length variation and neurodegenerationSemantic proximity Read ↗

ATXN2 intermediate expansions in amyotrophic lateral sclerosis.Semantic proximity Read ↗

Evaluation of polyglutamine repeats in autosomal dominant Parkinson's disease.Semantic proximity Read ↗

The modulation of Amyotrophic Lateral Sclerosis risk by ataxin-2 intermediate polyglutamine expansions is a specific effect.Semantic proximity Read ↗

PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeats.Semantic proximity Read ↗

Distinct TDP-43 pathology in ALS patients with ataxin 2 intermediate-length polyQ expansionsSemantic proximity Read ↗

Ataxin-2 polyQ expansions in FTLD-ALS spectrum disorders in Flanders-Belgian cohortsSemantic proximity Read ↗

Association of long ATXN2 CAG repeat sizes with increased risk of amyotrophic lateral sclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.