Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of long ATXN2 CAG repeat sizes with increased risk of amyotrophic lateral sclerosis.

Archives of neurology - 1 Jun 2011

Daoud Hussein, Belzil Véronique, Martins Sandra, Sabbagh Mike, Provencher Pierre, Lacomblez Lucette, Meininger Vincent, Camu William, Dupré Nicolas, Dion Patrick A, Rouleau Guy A

Abstract excerpt

OBJECTIVE: To analyze the ataxin 2 (ATXN2) CAG repeat size in a cohort of patients with amyotrophic lateral sclerosis (ALS) and healthy controls. Large (CAG)(n) alleles of the ATXN2 gene (27-33 repeats) were recently reported to be associated with an increased risk of ALS. DESIGN: Case-control study. SETTING: France and Quebec, Canada. PARTICIPANTS: A total of 556 case patients with ALS and 471 healthy controls;...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Amyotrophic Lateral Sclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ataxins

Share to Cohort Studies

Share to Genetic Linkage

Share to Nerve Tissue Proteins

Share to Spinocerebellar Ataxias

Share to Trinucleotide Repeat Expansion

Source

Identifiers

PMID: 21670397
DOI: 10.1001/archneurol.2011.111

Genes

ATXN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of long ATXN2 CAG repeat sizes with increased risk of amyotrophic lateral sclerosis.PMID 21670397Read ↗

Amyotrophic Lateral Sclerosis Risk for Spinocerebellar Ataxia Type 2 ATXN2 CAG Repeat AllelesSemantic proximity Read ↗

Expanded <i>ATXN2</i> CAG repeat size in ALS identifies genetic overlap between ALS and SCA2Semantic proximity Read ↗

ATXN2 trinucleotide repeat length correlates with risk of ALS.Semantic proximity Read ↗

Ataxin-2 repeat-length variation and neurodegenerationSemantic proximity Read ↗

Intermediate-length CAG repeat in ATXN2 is associated with increased risk for amyotrophic lateral sclerosis in Brazilian patients.Semantic proximity Read ↗

ATAXIN2 CAG-repeat length in Italian patients with amyotrophic lateral sclerosis: risk factor or variant phenotype? Implication for genetic testing and counseling.Semantic proximity Read ↗

Intermediate CAG repeat expansion in the ATXN2 gene is a unique genetic risk factor for ALS--a systematic review and meta-analysis of observational studies.Semantic proximity Read ↗

Assessment of <i>ATXN2</i> Repeat Expansion Length and Risk of ALS: A Meta-AnalysisSemantic proximity Read ↗

Intermediate-length polyglutamine in ATXN2 is a possible risk factor among Eastern Chinese patients with amyotrophic lateral sclerosis.Semantic proximity Read ↗

ATXN2 CAG repeat expansions increase the risk for Chinese patients with amyotrophic lateral sclerosisSemantic proximity Read ↗

Intermediate Repeat Expansion in the ATXN2 Gene as a Risk Factor in the ALS and FTD Spanish PopulationSemantic proximity Read ↗

Intermediate Repeat Expansion in ATXN2 Gene as a Risk Factor in ALS and FTD Spanish PopulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.