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Article

Quantitative diagnosis of malignant pleural effusions by single-cell mechanophenotyping.

Science translational medicine - 20 Nov 2013

Tse Henry T K, Gossett Daniel R, Moon Yo Sup, Masaeli Mahdokht, Sohsman Marie, Ying Yong, Mislick Kimberly, Adams Ryan P, Rao Jianyu, Di Carlo Dino

Abstract excerpt

Biophysical characteristics of cells are attractive as potential diagnostic markers for cancer. Transformation of cell state or phenotype and the accompanying epigenetic, nuclear, and cytoplasmic modifications lead to measureable changes in cellular architecture. We recently introduced a technique called deformability cytometry (DC) that enables rapid mechanophenotyping of single cells in suspension at rates of...

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PMID: 24259051
DOI: 10.1126/scitranslmed.3006559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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