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Article

Global Bidirectional Transcription of the Epstein-Barr Virus Genome during Reactivation

20 Nov 2013

Abstract excerpt

Epstein-Barr virus (EBV) reactivation involves the ordered induction of approximately 90 viral genes that participate in the generation of infectious virions. Using strand-specific RNA-seq to assess the EBV transcriptome during reactivation, we found extensive bidirectional transcription extending across nearly the entire genome. In contrast, only 4% of the EBV genome is currently bidirectionally annotated. Most...

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PMID: 24257595
DOI: 10.1128/jvi.02989-13

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