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A Genome-Wide Epstein-Barr Virus Polyadenylation Map and Its Antisense RNA to EBNA

24 Oct 2018

Abstract excerpt

Epstein-Barr virus represents an important human pathogen with an etiological role in the development of several cancers. By elucidation of a genome-wide polyadenylation landscape of EBV in JSC-1, Raji, and Akata cells, we have redefined the EBV transcriptome and mapped individual polymerase II (Pol II) transcripts of viral genes to each one of the mapped pA sites at single-nucleotide resolution as well as the...

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PMID: 30355690
DOI: 10.1128/jvi.01593-18

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