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Article

RNAs in Epstein–Barr virions control early steps of infection

27 Apr 2012

Abstract excerpt

Herpesviruses are dsDNA viruses, but their virions may additionally contain RNAs that can be transduced to recipient cells. The biological functions of herpes virion RNA species are unknown. Here we address this issue for EBV, a widespread human herpesvirus with oncogenic potential. We show that EBV-derived particles that include virions, virus-like particles, and subviral vesicles contain viral mRNAs, microRNAs,...

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PMID: 22543160
DOI: 10.1073/pnas.1115906109

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