Article
The genetic basis for individual differences in mRNA splicing and APOBEC1 editing activity in murine macrophages.
Genome research - 1 Mar 2014
Hassan Musa A, Butty Vincent, Jensen Kirk D C, Saeij Jeroen P J
Abstract excerpt
Alternative splicing and mRNA editing are known to contribute to transcriptome diversity. Although alternative splicing is pervasive and contributes to a variety of pathologies, including cancer, the genetic context for individual differences in isoform usage is still evolving. Similarly, although mRNA editing is ubiquitous and associated with important biological processes such as intracellular viral replication...
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