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Article

High levels of RNA-editing site conservation amongst 15 laboratory mouse strains.

Genome biology - 23 Apr 2012

Danecek Petr, Nellåker Christoffer, McIntyre Rebecca E, Buendia-Buendia Jorge E, Bumpstead Suzannah, Ponting Chris P, Flint Jonathan, Durbin Richard, Keane Thomas M, Adams David J

Abstract excerpt

BACKGROUND: Adenosine-to-inosine (A-to-I) editing is a site-selective post-transcriptional alteration of double-stranded RNA by ADAR deaminases that is crucial for homeostasis and development. Recently the Mouse Genomes Project generated genome sequences for 17 laboratory mouse strains and rich catalogues of variants. We also generated RNA-seq data from whole brain RNA from 15 of the sequenced strains. RESULTS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22524474
DOI: 10.1186/gb-2012-13-4-r26
PMCID: PMC3446300

Genes

ADAR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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