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Article

Incorporating alternative splicing and mRNA editing into the genetic analysis of complex traits.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Nov 2014

Hassan Musa A, Saeij Jeroen P J

Abstract excerpt

The nomination of candidate genes underlying complex traits is often focused on genetic variations that alter mRNA abundance or result in non-conservative changes in amino acids. Although inconspicuous in complex trait analysis, genetic variants that affect splicing or RNA editing can also generate proteomic diversity and impact genetic traits. Indeed, it is known that splicing and RNA editing modulate several...

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Identifiers

PMID: 25171292
DOI: 10.1002/bies.201400079
PMCID: PMC4280019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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