Article
The BRAF(V600E) mutation in papillary thyroid microcarcinoma: does the mutation have an impact on clinical outcome?
Clinical endocrinology - 1 Jun 2014
Walczyk Agnieszka, Kowalska Aldona, Kowalik Artur, Sygut Jacek, Wypiórkiewicz Elżbieta, Chodurska Renata, Pięciak Liliana, Góźdź Stanisław
Abstract excerpt
CONTEXT: An activating mutation in the gene BRAF has been correlated with poorer prognosis and more aggressive clinical course in papillary thyroid carcinoma (PTC). We therefore hypothesized that the good prognosis, high 5-year disease-free rate and high survival rate of patients with less aggressive papillary thyroid microcarcinoma (pT1aNo-x) would be associated with a lower incidence of the BRAF(V600E)...
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