Article
BRAF mutation in papillary thyroid carcinoma: predictive value for long-term prognosis and radioiodine sensitivity.
European annals of otorhinolaryngology, head and neck diseases - 1 Feb 2014
Zoghlami A, Roussel F, Sabourin J-C, Kuhn J-M, Marie J-P, Dehesdin D, Choussy O
Abstract excerpt
OBJECTIVES: BRAF pV600E mutation is the most common oncogenic event and the most specific mutation for papillary thyroid carcinoma (PTC). Many studies over the last decade have shown a direct relationship between BRAF mutation and aggressive tumour characteristics, resulting in poor prognosis. However, several recent studies have suggested that BRAF mutation is not associated with poor prognosis of PTC. The...
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