Article
The molecular pathogenesis of B-cell non-Hodgkin lymphoma.
European journal of haematology - 1 Oct 2015
Blombery Piers A, Wall Meaghan, Seymour John F
Abstract excerpt
The B-cell non-Hodgkin lymphomas (B-NHL) are a diverse group of haematological malignancies which arise from the mature B-lymphocyte compartment. Recently, our understanding of the molecular pathogenesis of these disorders has greatly increased due to technological advances such as high-throughput DNA sequencing techniques. A paradigm of B-NHL pathogenesis has emerged where the normal genetic processes that are...
Topics
- Animals
- Chromosome Aberrations
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- Lymphoma, B-Cell
- Lymphoma, Non-Hodgkin
- Mutation
- Oncogenes