Article
Association of microRNA-31 with BRAF mutation, colorectal cancer survival and serrated pathway.
Carcinogenesis - 1 Apr 2014
Nosho Katsuhiko, Igarashi Hisayoshi, Nojima Masanori, Ito Miki, Maruyama Reo, Yoshii Shinji, Naito Takafumi, Sukawa Yasutaka, Mikami Masashi, Sumioka Wakana, Yamamoto Eiichiro, Kurokawa Sei, Adachi Yasushi, Takahashi Hiroaki, Okuda Hiroyuki, Kusumi Takaya, Hosokawa Masao, Fujita Masahiro, Hasegawa Tadashi, Okita Kenji, Hirata Koichi, Suzuki Hiromu, Yamamoto Hiroyuki, Shinomura Yasuhisa
Abstract excerpt
BRAF is an important gene in colorectal cancers (CRCs) that is associated with molecular characterization and resistance to targeted therapy. Although microRNAs (miRNAs) are useful biomarkers of various cancers, the association between miRNA and BRAF in CRCs is undefined. Therefore, this study was conducted to identify a relationship between specific miRNA molecules and BRAF mutation in CRCs and serrated lesions....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.