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Article

A bacterial toxin inhibits DNA replication elongation through a direct interaction with the β sliding clamp.

Molecular cell - 12 Dec 2013

Aakre Christopher D, Phung Tuyen N, Huang David, Laub Michael T

Abstract excerpt

Toxin-antitoxin (TA) systems are ubiquitous on bacterial chromosomes, yet the mechanisms regulating their activity and the molecular targets of toxins remain incompletely defined. Here, we identify SocAB, an atypical TA system in Caulobacter crescentus. Unlike canonical TA systems, the toxin SocB...

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Share to Bacterial Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24239291
DOI: 10.1016/j.molcel.2013.10.014
PMCID: PMC3918436

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24239291-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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